GFRAL (NM_207410) Human Recombinant Protein

CAT#: TP710385

Purified recombinant protein of Human GDNF family receptor alpha like (GFRAL), with C-terminal His tag, secretory expressed in Sf9 cells, 20ug



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CNY 4,020.00


货期*
现货

规格
    • 20 ug

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经常一起买 (1)
Rabbit Polyclonal Anti-GFRAL Antibody
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC213001, encoding the region (19Ser-351Glu) of GFRAL.
Tag C-His
Predicted MW 37.8 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 150 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_997293
Locus ID 389400
UniProt ID Q6UXV0
Refseq Size 1911
Cytogenetics 6p12.1
Refseq ORF 1182
Synonyms bA360D14.1; C6orf144; GRAL; UNQ9356
Summary Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.[UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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