FH (NM_000143) Human Recombinant Protein
CAT#: TP720199XL
Recombinant protein of human fumarate hydratase (FH), nuclear gene encoding mitochondrial protein
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CNY 26,600.00
货期*
2周
规格
经常一起买 (1)
FH (Fumarate Hydratase) mouse monoclonal antibody, clone OTI1F10 (formerly 1F10)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Ala45-Lys510
|
Tag | Tag Free |
Predicted MW | 50.2 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris, pH 8.0. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_000134 |
Locus ID | 2271 |
UniProt ID | P07954, A0A0S2Z4C3 |
Cytogenetics | 1q43 |
Synonyms | FMRD; HLRCC; HsFH; LRCC; MCL; MCUL1 |
Summary | The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Citrate cycle (TCA cycle), Metabolic pathways, Pathways in cancer, Renal cell carcinoma |
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