CD55 (NM_000574) Human Recombinant Protein
CAT#: TP720284
Recombinant protein of human CD55 molecule, decay accelerating factor for complement (Cromer blood group) (CD55), transcript variant 1
View other "CD55" proteins (4)
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CNY 3,140.00
Cited in 1 publication. |
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Asp35-Ser353
|
Tag | C-His |
Predicted MW | 36.0 kDa |
Concentration | lot specific |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
Reference Data | |
RefSeq | NP_000565 |
Locus ID | 1604 |
UniProt ID | P08174 |
Cytogenetics | 1q32.2 |
Synonyms | CHAPLE; CR; CROM; DAF; TC |
Summary | This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014] |
Protein Families | Druggable Genome |
Protein Pathways | Complement and coagulation cascades, Hematopoietic cell lineage, Viral myocarditis |
Citations (1)
The use of this Proteins has been cited in the following citations: |
---|
Mutation of complement factor B causing massive fluid-phase dysregulation of the alternative complement pathway can result in atypical hemolytic uremic syndrome
,Zhang, Y;Kremsdorf, R;Sperati, CJ;Henriksen, KJ;Mori, M;Goodfellow, RX;Pitcher, GR;Benson, C;Borsa, NG;Taylor, RP;Nester, CM;Smith, RJ;,
Kidney Int.
,PubMed ID 32540405
[CD55]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC424635 | CD55 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC426508 | CD55 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY424635 | Transient overexpression lysate of CD55 molecule, decay accelerating factor for complement (Cromer blood group) (CD55), transcript variant 1 |
CNY 3,080.00 |
|
LY426508 | Transient overexpression lysate of CD55 molecule, decay accelerating factor for complement (Cromer blood group) (CD55), transcript variant 2 |
CNY 3,080.00 |