D Amino Acid Oxidase (DAO) (NM_001917) Human Recombinant Protein
CAT#: TP720849L
Purified recombinant protein of Human D-amino-acid oxidase (DAO)
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CNY 18,030.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
Met1-Leu347
|
Tag | N-His |
Predicted MW | 41.64 kDa |
Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | Supplied as a 0.2 um filtered solution of 20mM Tris-HCl,20%Glycerol,1mM DTT,2mM EDTA,Ph8.0. |
Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
Reference Data | |
RefSeq | NP_001908 |
Locus ID | 1610 |
UniProt ID | P14920, A0A024RBI1 |
Refseq Size | 1576 |
Cytogenetics | 12q24.11 |
Refseq ORF | 1041 |
Synonyms | DAAO; DAMOX; OXDA |
Summary | This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome |
Protein Pathways | Arginine and proline metabolism, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways |
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