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CD14 (NM_000591) Human Recombinant Protein
CAT＃: TP723883
Purified recombinant protein of Human CD14 molecule (CD14), transcript variant 1
View other "CD14" proteins (9)
|
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CNY 3,210.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | CHO |
| Expression cDNA Clone or AA Sequence |
Human CD14, the region of Thr20-Cys352, from gene Accession# NM_000591
|
| Tag | Tag Free |
| Predicted MW | 35.8 kDa |
| Concentration | lot specific |
| Purity | >95%, as determined by Coomassie stained SDS-PAGE. |
| Buffer | 1 x PBS, pH 7.2 |
| Storage | Store at -80°C. |
| Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Bioactivity | The ED50 is 100-400 ng/ml, corresponding to a specific activity of 1.0-2.5 x 104 units/mg, determined by production of IL-8 from THP-1 cells trated with LPS (2 ng/ml) and CD14. |
| Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
| Reference Data | |
| RefSeq | NP_000582 |
| Locus ID | 929 |
| UniProt ID | P08571 |
| Refseq Size | 1623 |
| Cytogenetics | 5q31.3 |
| Refseq ORF | 1125 |
| Summary | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] |
| Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage, MAPK signaling pathway, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Toll-like receptor signaling pathway |
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC421877 | CD14 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC424624 | CD14 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY421877 | Transient overexpression lysate of CD14 molecule (CD14), transcript variant 2 |
CNY 3,080.00 |
|
| LY424624 | Transient overexpression lysate of CD14 molecule (CD14), transcript variant 1 |
CNY 3,080.00 |
|
| PH303819 | CD14 MS Standard C13 and N15-labeled recombinant protein (NP_000582) |
CNY 19,520.00 |
|
| PH318181 | CD14 MS Standard C13 and N15-labeled recombinant protein (NP_001035110) |
CNY 19,520.00 |
|
| TP303819 | Recombinant protein of human CD14 molecule (CD14), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP318181 | Recombinant protein of human CD14 molecule (CD14), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP700277 | Purified recombinant protein of human CD14 molecule (CD14), transcript variant 1, with C-terminal Fc tag, expressed in human cells, 20 µg |
CNY 6,650.00 |
