Human IFNAR2 Protein, hFc Tag

Specifications

Product Data
Expression Host	HEK293
Tag	C-Human Fc
Predicted MW	The protein has a predicted molecular mass of 50.9 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR2-hFc is approximately 55-70 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Stability	12 months from date of despatch
Reference Data
Synonyms	IFN-alpha-REC, IFN-R, IFNABR, IFNARB, IMD45
Summary	The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45. [provided by RefSeq, Jul 2020]

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