Cynomolgus Recombinant Protein
CAT#: TP724749
Recombinant Cynomolgus IL-23R (C-hFc)
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CNY 3,140.00
货期*
2周
规格
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Specifications
Product Data | |
Species | Cynomolgus |
Protein Source | Human |
Expression cDNA Clone or AA Sequence |
Met1-Asp353
|
Tag | C-Human Fc |
Buffer | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Note | Recombinant Cynomolgus IL-23R (C-hFc) is produced by Human Cells. The target gene encoding Met1-Asp353 is expressed with a C-hFc tag. |
Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Synonyms | IL23R,IL-23 Receptor |
Summary | Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
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