Human Recombinant Protein

CAT#: TP724793

Recombinant Human Mucin-1 (C-hFc)



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CNY 3,140.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Species Human
Protein Source Human 293
Expression cDNA Clone or AA Sequence
Tag C-hFc
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Note Recombinant Human Mucin-1 is produced by our Mammalian expression system and the target gene encoding Ser33-Gly167 is expressed with a Fc tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Synonyms Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3;Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD227; MUC1
Summary Mucin-1 (MUC1) is a membrane-bound protein that belongs to the mucin family. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. It is expressed on the apical surface of epithelial cells that line the mucosal surfaces of various tissues including lung, breast stomach and pancreas. MUC1 plays an important role in forming protective mucous barriers on epithelial surfaces. It is also involved in intracellular signaling. MUC-1 promotes tumor progression and regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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