CD47 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human 293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Gln19-Pro139
Tag	C-6His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Note	Recombinant Human CD47 is produced by Human 293 Cells. The target gene encoding Gln19-Pro139 is expressed with a 6His tag at the C terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	961
UniProt ID	Q08722
Synonyms	Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-AssociatedProtein; IAP; Protein MER6; CD47; MER6
Summary	Leukocyte surface antigen CD47 belongs to the immunoglobulin superfamily. It is broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets and in the modulation of integrins. It may prevent premature elimination of red blood cells and is involved in membrane permeability changes induced following virus infection. CD47 also plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity.
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	ECM-receptor interaction

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