NELFE Human Recombinant Protein
CNY 3,140.00
货期*
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Specifications
Product Data | |
Species | Human |
Protein Source | E. coli |
Expression cDNA Clone or AA Sequence |
I4-F380
|
Tag | C-His |
Buffer | Supplied as a 0.2 um filtered solution of 500mM PBS, 300mM NaCl, 10%Glycerol, pH7.4 |
Note | MADE TO ORDER | Recombinant Human NELF-E is produced by E.coli expression system and the target gene encoding I4-F380 is expressed with a His tag at the C-terminus. |
Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 7936 |
UniProt ID | P18615 |
Synonyms | Negative elongation factor E; RNA-binding protein RD |
Summary | Negative elongation factor complex member E is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Provides the strongest RNA binding activity of the NELF complex and may initially recruit the NELF complex to RNA. |
Protein Families | Transcription Factors |
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