Cadm1 Mouse Recombinant Protein

CAT#: TP726874

Recombinant Mouse Cell Adhesion Molecule 1/CADM1/IGSF4A/SynCAM1 (C-Fc)



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CNY 3,140.00


货期*
2周

规格
    • 10 ug

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经常一起买 (1)
Goat Anti-CADM1/TSLC1 Antibody
    • 100 ug

CNY 5,371.00

Specifications

Product Data
Species Mouse
Protein Source Human
Expression cDNA Clone or AA Sequence
Tag C-Fc
Buffer Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note Recombinant Mouse Cell adhesion molecule 1 is produced by our Mammalian expression system and the target gene encoding Gln48-His388 is expressed with a Fc tag at the C-terminus.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability 12 months from date of despatch
Reference Data
Locus ID 54725
UniProt ID Q8R5M8
Synonyms Cell adhesion molecule 1;Immunoglobulin superfamily member 4;IgSF4;Nectin-like protein 2;NECL-2;Synaptic cell adhesion molecule;SynCAM;Tumor suppressor in lung cancer 1;TSLC-1
Summary Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. CADM1 may contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, it may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. The protein acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly. It may be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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