SOD2 Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Lys25-Lys222
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Note	Recombinant Human Superoxide Dismutase [Mn] Mitochondrial is produced by our Mammalian expression system and the target gene encoding Lys25-Lys222 is expressed with a 6His tag at the C-terminus.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	6648
UniProt ID	P04179
Synonyms	Superoxide Dismutase [Mn] Mitochondrial; SOD2
Summary	Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Huntington's disease

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