TAG1 (CNTN2) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Ser31-Asn1012
Tag	C-His
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Note	Recombinant Human Transient axonal glycoprotein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Asn1012 is expressed with a 6His tag at the C-terminus.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	12 months from date of despatch
Reference Data
Locus ID	6900
UniProt ID	Q02246
Synonyms	Contactin-2; Axonal glycoprotein TAG-1; Axonin-1; Transient axonal glycoprotein 1; CNTN2; AXT; TAG1; TAX1
Summary	Contactin-2 (CNTN2) is encoded by the CNTN2 gene,which belongs to the immunoglobulin superfamily and contactin family. It contains 4 fibronectin type-III domains and 6 Ig-like C2-type domains. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. CNTN2 may play a role in the formation of axon connections in the developing nervous system. In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
Protein Pathways	Cell adhesion molecules (CAMs)

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