TXNDC4 (ERP44) Human Recombinant Protein

Specifications

Product Data
Species	Human
Protein Source	Human
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Glu30-Asp402
Tag	C-His
Buffer	Supplied as a 0.2 um filtered solution of 20mM Tris HCl, 10% Glycerol, pH 7.5.
Note	Recombinant Human ER resident protein 44 is produced by our Mammalian expression system and the target gene encoding Glu30-Asp402 is expressed with a 6His tag at the C-terminus.
Storage	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Stability	12 months from date of despatch
Reference Data
Locus ID	23071
UniProt ID	Q9BS26
Synonyms	Thioredoxin domain-containing protein 4; ER protein 44; KIAA0573; TXNDC4
Summary	Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Protein Families	Druggable Genome

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