IL1 alpha (IL1A) Human Recombinant Protein
CNY 3,500.00
货期*
2周
规格
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经常一起买 (1)
IL1A mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
CNY 1,999.00
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Specifications
Product Data | |
Species | Human |
Expression cDNA Clone or AA Sequence |
Ser113-Ala271
|
Tag | C-Avi |
Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. |
Note | Biotinylated Recombinant Human Interleukin-1 alpha is produced by our E.coli expression system and the target gene encoding Ser113-Ala271 is expressed with a Avi tag at the C-terminus. |
Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Stability | 12 months from date of despatch |
Reference Data | |
Locus ID | 3552 |
UniProt ID | P01583 |
Synonyms | Interleukin-1 Alpha; IL-1 Alpha; Hematopoietin-1; IL1A; IL1F1 |
Summary | Interleukin-1 alpha (IL1α) is a cytokine member of the interleukin-1 family. IL-1 consists of two distinct forms: IL1α and IL1β that recognize the same cell surface receptors but are distinct proteins with approximately 25% amino acid sequence identity. IL1α is constitutively produced by epithelial cells and plays an essential role in maintenance of skin barrier function. Upon stimulation, a wide variety of cells including osteoblasts, monocytes, macrophages can be induced to express IL1α. IL1α possesses a wide range of metabolic, physiological, haematopoietic activities, and is critically involved in the regulation of the immune responses and inflammatory responses. |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus |
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