CD8A (NM_001145873) Human Recombinant Protein
CAT#: TP761250
Purified recombinant protein of Human CD8a molecule (CD8A), transcript variant 3, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
View other "CD8A" proteins (13)
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CNY 2,040.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding human full-length CD8A
|
Tag | N-His |
Predicted MW | 23.5 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_001139345 |
Locus ID | 925 |
UniProt ID | P01732 |
Refseq Size | 3177 |
Cytogenetics | 2p11.2 |
Refseq ORF | 705 |
Synonyms | CD8; Leu2; p32 |
Summary | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] |
Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
Protein Pathways | Antigen processing and presentation, Cell adhesion molecules (CAMs), Hematopoietic cell lineage, Primary immunodeficiency, T cell receptor signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC403530 | CD8A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC419749 | CD8A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC429040 | CD8A HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY403530 | Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 2 |
CNY 3,080.00 |
|
LY419749 | Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 1 |
CNY 3,080.00 |
|
LY429040 | Transient overexpression lysate of CD8a molecule (CD8A), transcript variant 3 |
CNY 3,080.00 |
|
TP721308 | Human CD8α Protein (C-His) |
CNY 2,450.00 |
|
TP721309 | Human CD8α Protein (C-His-Avi) |
CNY 2,450.00 |
|
TP721310 | Biotinylated Human CD8α Protein (C-His-Avi) |
CNY 3,480.00 |
|
TP721311 | PE Conjugated Human CD8α Protein (C-His) |
CNY 3,480.00 |
|
TP721312 | APC Conjugated Human CD8α Protein (C-His) |
CNY 3,480.00 |
|
TP760215 | Recombinant protein of human CD8a molecule (CD8A), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |
|
TP761244 | Purified recombinant protein of Human CD8a molecule (CD8A), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug |
CNY 2,040.00 |