TTF1 (NKX2-1) (NM_003317) Human Recombinant Protein
CAT#: TP762371
Purified recombinant protein of Human NK2 homeobox 1 (NKX2-1), transcript variant 2, Met1-Pro123, with N-terminal His tag, expressed in E.coli, 50ug
View other "TTF1" proteins (5)
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CNY 1,950.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
A DNA sequence encoding the region(Met1-Pro123) of TTF1
|
Tag | N-His |
Predicted MW | 12.8 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 50 mM Tris-HCl, pH 8.0, 8 M urea |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C after receiving vials. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_003308 |
Locus ID | 7080 |
UniProt ID | P43699 |
Refseq Size | 2352 |
Cytogenetics | 14q13.3 |
Refseq ORF | 1113 |
Synonyms | BCH; BHC; NK-2; NKX2.1; NKX2A; NMTC1; T/EBP; TEBP; TITF1; TTF-1; TTF1 |
Summary | This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014] |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401141 | NKX2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC421530 | NKX2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY401141 | Transient overexpression lysate of NK2 homeobox 1 (NKX2-1), transcript variant 2 |
CNY 3,080.00 |
|
LY421530 | Transient overexpression lysate of NK2 homeobox 1 (NKX2-1), transcript variant 1 |
CNY 3,080.00 |
|
TP762355 | Purified recombinant protein of Human NK2 homeobox 1 (NKX2-1), transcript variant 2, Gly89-Pro123-GGGGS-Leu156-His193, with N-terminal His tag, expressed in E.coli, 50ug |
CNY 1,950.00 |