United States
Germany
Japan
United Kingdom
China
GSK3 alpha (GSK3A) Rabbit Polyclonal Antibody
CAT＃: TA322277S
Anti-GSK3A Rabbit Polyclonal Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1,280.00
Product images
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 458-467 amino acids of Human glycogen synthase kinase 3 alpha |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | glycogen synthase kinase 3 alpha |
| Database Link | |
| Background | This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase; and transcription factors; such as JUN. It also plays a role in the WNT and PI3K signaling pathways; as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling; regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. |
| Synonyms | DKFZp686D0638 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
其它GSK3 alpha产品
