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CEMIP2 (NM_001135820) Human Tagged ORF Clone
CAT＃: RG227939
- TrueORF®
TMEM2 (tGFP-tagged) - Human transmembrane protein 2 (TMEM2), transcript variant 2
ORF Plasmid: DDK
"NM_001135820" in other vectors (4)
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CNY 11,712.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | TMEM2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG227939 representing NM_001135820
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTATGCCACTGATTCCAGGGGACACTCCCCTGCTTTCCTCCAACCTCAGAATGGAAATAGTCGTCACC CATCTGGCTATGTTCCAGGGAAGGTTGTCCCATTGCGTCCCCCTCCTCCTCCAAAGAGTCAAGCTTCAGC CAAATTTACCTCCATCAGACGAGAAGACCGGGCAACCTTCGCATTCTCACCTGAAGAACAGCAAGCCCAG AGAGAAAGTCAAAAGCAAAAGAGACACAAAAATACTTTCATTTGTTTTGCTATTACTAGTTTCTCATTTT TTATTGCACTTGCAATCATTTTAGGAATATCCTCAAAATATGCTCCAGATGAAAATTGCCCAGATCAAAA TCCTCGTCTCAGGAATTGGGATCCAGGACAAGATTCTGCAAAGCAAGTTGTTATCAAGGAGGGAGATATG CTCCGTCTGACCTCAGACGCCACCGTGCATTCTATAGTCATTCAGGATGGAGGACTGCTTGTATTTGGGG ACAATAAAGATGGATCCAGAAATATTACTTTGAGGACTCATTACATCCTGATCCAGGATGGTGGGGCGCT TCATATTGGAGCAGAAAAATGCCGCTATAAATCCAAAGCGACAATTACCTTGTATGGCAAGTCAGATGAA GGTGAAAGTATGCCAACATTTGGCAAAAAGTTTATTGGTGTGGAAGCTGGCGGGACACTGGAGTTACATG GGGCACGGAAGGCATCGTGGACGTTGTTGGCAAGGACCCTGAATTCCTCAGGCTTGCCCTTTGGGTCCTA TACCTTTGAAAAGGACTTTTCCCGGGGCCTCAATGTGAGGGTCATTGACCAAGACACGGCCAAAATTTTG GAAAGTGAGAGATTTGATACCCATGAATACCGCAATGAGAGCAGGCGGCTTCAGGAGTTTCTGAGATTCC AGGATCCAGGTCGGATTGTTGCCATAGCTGTCGGGGATTCAGCCGCTAAAAGTCTCTTACAAGGAACCAT CCAGATGATCCAGGAACGGTTGGGAAGTGAACTGATCCAAGGACTGGGCTACAGGCAAGCTTGGGCTTTA GTTGGTGTCATTGATGGTGGAAGCACTTCTTGCAATGAATCCGTGAGAAACTATGAAAATCATAGCAGTG GCGGGAAGGCTCTTGCCCAAAGAGAATTTTATACTGTGGATGGCCAGAAGTTCTCTGTGACAGCTTATAG TGAATGGATTGAAGAAACCCCTCAGTTCCTGCACATGGGTGAGATCATAGACGGTGTAGACATGAGAGCT GAGGTTGGAATTCTTACCCGGAATATTGTGATCCAAGGAGAAGTGGAGGACTCATGCTACGCAGAAAATC AGTGCCAATTTTTTGATTATGATACCTTTGGGGGACACATTATGATAATGAAAAATTTTACTTCAGTCCA TCTTTCTTATGTGGAATTGAAACACATGGGTCAGCAGCAGATGGGGCGATACCCTGTTCATTTTCACCTG TGTGGTGACGTGGATTATAAAGGAGGATACAGACATGCAACATTTGTGGACGGCCTGTCTATTCATCACA GCTTCTCAAGGTGCATCACTGTGCATGGGACAAATGGCTTGCTAATAAAAGACACCATTGGGTTTGACAC ACTAGGTCATTGTTTCTTTTTGGAAGATGGTATTGAACAGAGGAATACTTTGTTCCACAATCTGGGACTC CTCACCAAGCCGGGTACTCTCCTGCCCACCGATAGGAACAACTCCATGTGTACCACCATGCGAGATAAAG TGTTTGGAAATTACATTCCTGTGCCTGCTACTGACTGTATGGCTGTTTCAACTTTCTGGATTGCTCATCC CAACAATAATCTGATTAATAATGCAGCTGCAGGCTCACAGGATGCTGGAATATGGTATTTATTCCACAAG GAACCAACTGGGGAATCCAGTGGATTGCAGCTCTTGGCAAAACCAGAACTCACTCCATTGGGTATATTTT ATAACAACAGGGTCCATTCAAATTTTAAGGCTGGCTTATTTATTGACAAAGGTGTCAAAACAACCAACTC TAGTGCTGCTGACCCAAGGGAATACCTCTGTTTGGACAATAGTGCAAGATTTCGACCTCATCAGGATGCA AACCCCGAAAAACCACGTGTTGCTGCTCTAATTGACAGGCTCATTGCTTTTAAAAATAATGATAATGGAG CTTGGGTCAGAGGAGGAGATATTATCGTTCAAAATTCAGCATTTGCAGATAATGGAATAGGACTGACCTT TGCCAGTGATGGAAGCTTCCCAAGTGATGAAGGTTCCAGCCAAGAGGTATCTGAATCTCTCTTTGTTGGG GAGAGCAGGAATTACGGCTTTCAGGGTGGTCAGAACAAGTATGTAGGCACTGGAGGAATAGACCAGAAGC CTCGAACATTACCCAGGAACAGGACGTTCCCAATTAGAGGCTTTCAGATTTATGATGGGCCCATTCATCT CACAAGGAGCACTTTCAAAAAATATGTGCCAACTCCAGATAGGTACAGCAGTGCAATTGGCTTCCTCATG AAGAATTCCTGGCAGATAACCCCCAGGAATAATATCTCCCTCGTGAAGTTTGGTCCACATGTCTCTCTGA ATGTCTTTTTTGGAAAGCCTGGTCCCTGGTTTGAAGATTGTGAGATGGATGGTGATAAGAACTCCATATT CCATGACATTGATGGCTCTGTGACAGGATACAAGGATGCTTATGTGGGAAGAATGGACAACTACCTGATC CGCCATCCAAGCTGTGTAAATGTGTCTAAGTGGAATGCAGTGATCTGCAGTGGGACCTATGCACAGGTCT ATGTACAGACATGGAGCACTCAGAATCTTTCTATGACCATTACACGAGATGAGTATCCGTCCAACCCTAT GGTGCTCCGAGGTATTAATCAGAAGGCTGCCTTTCCACAGTACCAGCCTGTCGTCATGCTGGAGAAGGGT TATACCATCCACTGGAATGGGCCGGCACCACGGACTACATTTCTATACCTCGTCAACTTCAACAAGAATG ACTGGATTCGAGTTGGCCTTTGCTATCCATCAAACACAAGTTTTCAAGTTACCTTTGGCTATTTGCAGCG GCAGAATGGCTCATTATCCAAAATCGAAGAATATGAGCCTGTGCATTCACTGGAAGAACTGCAAAGAAAG CAATCCGAGAGGAAATTCTATTTTGACTCCAGCACGGGGTTACTGTTTTTGTATCTCAAAGCCAAAAGCC ACAGGCATGGCCACAGTTACTGTTCATCTCAGGGATGTGAAAGAGTCAAGATCCAAGCAGCCACAGACTC AAAGGACATCAGTAACTGCATGGCCAAAGCATACCCACAGTACTACAGAAAGCCGTCAGTGGTCAAGCGG ATGCCGGCCATGCTCACTGGACTCTGTCAAGGCTGTGGCACTCGGCAGGTGGTGTTTACTAGTGATCCTC ATAAAAGTTACCTCCCTGTGCAATTCCAGTCACCTGATAAAGCAGAAACCCAGCGTGGAGACCCGTCTGT TATTTCTGTCAATGGCACTGACTTTACCTTCCGAAGTGCAGGCGTCCTCCTCCTTGTTGTGGATCCGTGC AGCGTTCCATTCCGCTTGACGGAAAAAACGGTTTTTCCTCTTGCTGATGTCAGTCGCATTGAAGAGTATT TAAAAACAGGCATCCCTCCAAGGTCCATTGTTCTGTTGAGCACAAGAGGAGAAATAAAGCAGTTAAACAT TTCACACTTACTAGTACCTCTGGGATTAGCCAAACCAGCTCATCTTTATGACAAAGGGAGTACCATATTT TTGGGATTCAGTGGAAACTTTAAACCATCATGGACTAAGCTATTTACCAGTCCTGCTGGACAGGGCCTTG GGGTGCTTGAACAATTCATACCTTTGCAGCTGGACGAATATGGTTGTCCCAGAGCCACCACTGTCCGCAG AAGAGACCTGGAACTGCTAAAGCAAGCTTCAAAAGCACAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG227939 representing NM_001135820
Red=Cloning site Green=Tags(s) MYATDSRGHSPAFLQPQNGNSRHPSGYVPGKVVPLRPPPPPKSQASAKFTSIRREDRATFAFSPEEQQAQ RESQKQKRHKNTFICFAITSFSFFIALAIILGISSKYAPDENCPDQNPRLRNWDPGQDSAKQVVIKEGDM LRLTSDATVHSIVIQDGGLLVFGDNKDGSRNITLRTHYILIQDGGALHIGAEKCRYKSKATITLYGKSDE GESMPTFGKKFIGVEAGGTLELHGARKASWTLLARTLNSSGLPFGSYTFEKDFSRGLNVRVIDQDTAKIL ESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLLQGTIQMIQERLGSELIQGLGYRQAWAL VGVIDGGSTSCNESVRNYENHSSGGKALAQREFYTVDGQKFSVTAYSEWIEETPQFLHMGEIIDGVDMRA EVGILTRNIVIQGEVEDSCYAENQCQFFDYDTFGGHIMIMKNFTSVHLSYVELKHMGQQQMGRYPVHFHL CGDVDYKGGYRHATFVDGLSIHHSFSRCITVHGTNGLLIKDTIGFDTLGHCFFLEDGIEQRNTLFHNLGL LTKPGTLLPTDRNNSMCTTMRDKVFGNYIPVPATDCMAVSTFWIAHPNNNLINNAAAGSQDAGIWYLFHK EPTGESSGLQLLAKPELTPLGIFYNNRVHSNFKAGLFIDKGVKTTNSSAADPREYLCLDNSARFRPHQDA NPEKPRVAALIDRLIAFKNNDNGAWVRGGDIIVQNSAFADNGIGLTFASDGSFPSDEGSSQEVSESLFVG ESRNYGFQGGQNKYVGTGGIDQKPRTLPRNRTFPIRGFQIYDGPIHLTRSTFKKYVPTPDRYSSAIGFLM KNSWQITPRNNISLVKFGPHVSLNVFFGKPGPWFEDCEMDGDKNSIFHDIDGSVTGYKDAYVGRMDNYLI RHPSCVNVSKWNAVICSGTYAQVYVQTWSTQNLSMTITRDEYPSNPMVLRGINQKAAFPQYQPVVMLEKG YTIHWNGPAPRTTFLYLVNFNKNDWIRVGLCYPSNTSFQVTFGYLQRQNGSLSKIEEYEPVHSLEELQRK QSERKFYFDSSTGLLFLYLKAKSHRHGHSYCSSQGCERVKIQAATDSKDISNCMAKAYPQYYRKPSVVKR MPAMLTGLCQGCGTRQVVFTSDPHKSYLPVQFQSPDKAETQRGDPSVISVNGTDFTFRSAGVLLLVVDPC SVPFRLTEKTVFPLADVSRIEEYLKTGIPPRSIVLLSTRGEIKQLNISHLLVPLGLAKPAHLYDKGSTIF LGFSGNFKPSWTKLFTSPAGQGLGVLEQFIPLQLDEYGCPRATTVRRRDLELLKQASKAH TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001135820 |
| ORF Size | 3960 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001135820.2 |
| RefSeq Size | 6351 bp |
| RefSeq ORF | 3963 bp |
| Locus ID | 23670 |
| UniProt ID | Q9UHN6 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227939 | TMEM2 (Myc-DDK-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 13,210.00 |
|
| RC227939L3 | Lenti-ORF clone of TMEM2 (Myc-DDK-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 15,110.00 |
|
| RC227939L4 | Lenti-ORF clone of TMEM2 (mGFP-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 15,110.00 |
|
| SC325411 | TMEM2 (untagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 10,450.00 |
