TMEM2 (CEMIP2) (NM_001135820) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC227939L3V

  • LentiORF®

Lenti ORF particles, TMEM2 (Myc-DDK-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 11,210.00


货期*
详询

规格
    • 200 ul

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Specifications

Product Data
Product Name TMEM2 (CEMIP2) (NM_001135820) Human Tagged ORF Clone Lentiviral Particle
Synonyms TMEM2
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN NM_001135820
ORF Size 3960 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC227939).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_001135820.1
RefSeq ORF 3963 bp
Locus ID 23670
Protein Families Transmembrane
MW 147.3 kDa
Gene Summary This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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