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CEMIP2 (NM_001135820) Human Untagged Clone
CAT＃: SC325411
TMEM2 (untagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TMEM2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001135820, the custom clone sequence may differ by one or more nucleotides
ATGTATGCCACTGATTCCAGGGGACACTCCCCTGCTTTCCTCCAACCTCAGAATGGAAAT AGTCGTCACCCATCTGGCTATGTTCCAGGGAAGGTTGTCCCATTGCGTCCCCCTCCTCCT CCAAAGAGTCAAGCTTCAGCCAAATTTACCTCCATCAGACGAGAAGACCGGGCAACCTTC GCATTCTCACCTGAAGAACAGCAAGCCCAGAGAGAAAGTCAAAAGCAAAAGAGACACAAA AATACTTTCATTTGTTTTGCTATTACTAGTTTCTCATTTTTTATTGCACTTGCAATCATT TTAGGAATATCCTCAAAATATGCTCCAGATGAAAATTGCCCAGATCAAAATCCTCGTCTC AGGAATTGGGATCCAGGACAAGATTCTGCAAAGCAAGTTGTTATCAAGGAGGGAGATATG CTCCGTCTGACCTCAGACGCCACCGTGCATTCTATAGTCATTCAGGATGGAGGACTGCTT GTATTTGGGGACAATAAAGATGGATCCAGAAATATTACTTTGAGGACTCATTACATCCTG ATCCAGGATGGTGGGGCGCTTCATATTGGAGCAGAAAAATGCCGCTATAAATCCAAAGCG ACAATTACCTTGTATGGCAAGTCAGATGAAGGTGAAAGTATGCCAACATTTGGCAAAAAG TTTATTGGTGTGGAAGCTGGCGGGACACTGGAGTTACATGGGGCACGGAAGGCATCGTGG ACGTTGTTGGCAAGGACCCTGAATTCCTCAGGCTTGCCCTTTGGGTCCTATACCTTTGAA AAGGACTTTTCCCGGGGCCTCAATGTGAGGGTCATTGACCAAGACACGGCCAAAATTTTG GAAAGTGAGAGATTTGATACCCATGAATACCGCAATGAGAGCAGGCGGCTTCAGGAGTTT CTGAGATTCCAGGATCCAGGTCGGATTGTTGCCATAGCTGTCGGGGATTCAGCCGCTAAA AGTCTCTTACAAGGAACCATCCAGATGATCCAGGAACGGTTGGGAAGTGAACTGATCCAA GGACTGGGCTACAGGCAAGCTTGGGCTTTAGTTGGTGTCATTGATGGTGGAAGCACTTCT TGCAATGAATCCGTGAGAAACTATGAAAATCATAGCAGTGGCGGGAAGGCTCTTGCCCAA AGAGAATTTTATACTGTGGATGGCCAGAAGTTCTCTGTGACAGCTTATAGTGAATGGATT GAAGAAACCCCTCAGTTCCTGCACATGGGTGAGATCATAGACGGTGTAGACATGAGAGCT GAGGTTGGAATTCTTACCCGGAATATTGTGATCCAAGGAGAAGTGGAGGACTCATGCTAC GCAGAAAATCAGTGCCAATTTTTTGATTATGATACCTTTGGGGGACACATTATGATAATG AAAAATTTTACTTCAGTCCATCTTTCTTATGTGGAATTGAAACACATGGGTCAGCAGCAG ATGGGGCGATACCCTGTTCATTTTCACCTGTGTGGTGACGTGGATTATAAAGGAGGATAC AGACATGCAACATTTGTGGACGGCCTGTCTATTCATCACAGCTTCTCAAGGTGCATCACT GTGCATGGGACAAATGGCTTGCTAATAAAAGACACCATTGGGTTTGACACACTAGGTCAT TGTTTCTTTTTGGAAGATGGTATTGAACAGAGGAATACTTTGTTCCACAATCTGGGACTC CTCACCAAGCCGGGTACTCTCCTGCCCACCGATAGGAACAACTCCATGTGTACCACCATG CGAGATAAAGTGTTTGGAAATTACATTCCTGTGCCTGCTACTGACTGTATGGCTGTTTCA ACTTTCTGGATTGCTCATCCCAACAATAATCTGATTAATAATGCAGCTGCAGGCTCACAG GATGCTGGAATATGGTATTTATTCCACAAGGAACCAACTGGGGAATCCAGTGGATTGCAG CTCTTGGCAAAACCAGAACTCACTCCATTGGGTATATTTTATAACAACAGGGTCCATTCA AATTTTAAGGCTGGCTTATTTATTGACAAAGGTGTCAAAACAACCAACTCTAGTGCTGCT GACCCAAGGGAATACCTCTGTTTGGACAATAGTGCAAGATTTCGACCTCATCAGGATGCA AACCCCGAAAAACCACGTGTTGCTGCTCTAATTGACAGGCTCATTGCTTTTAAAAATAAT GATAATGGAGCTTGGGTCAGAGGAGGAGATATTATCGTTCAAAATTCAGCATTTGCAGAT AATGGAATAGGACTGACCTTTGCCAGTGATGGAAGCTTCCCAAGTGATGAAGGTTCCAGC CAAGAGGTATCTGAATCTCTCTTTGTTGGGGAGAGCAGGAATTACGGCTTTCAGGGTGGT CAGAACAAGTATGTAGGCACTGGAGGAATAGACCAGAAGCCTCGAACATTACCCAGGAAC AGGACGTTCCCAATTAGAGGCTTTCAGATTTATGATGGGCCCATTCATCTCACAAGGAGC ACTTTCAAAAAATATGTGCCAACTCCAGATAGGTACAGCAGTGCAATTGGCTTCCTCATG AAGAATTCCTGGCAGATAACCCCCAGGAATAATATCTCCCTCGTGAAGTTTGGTCCACAT GTCTCTCTGAATGTCTTTTTTGGAAAGCCTGGTCCCTGGTTTGAAGATTGTGAGATGGAT GGTGATAAGAACTCCATATTCCATGACATTGATGGCTCTGTGACAGGATACAAGGATGCT TATGTGGGAAGAATGGACAACTACCTGATCCGCCATCCAAGCTGTGTAAATGTGTCTAAG TGGAATGCAGTGATCTGCAGTGGGACCTATGCACAGGTCTATGTACAGACATGGAGCACT CAGAATCTTTCTATGACCATTACACGAGATGAGTATCCGTCCAACCCTATGGTGCTCCGA GGTATTAATCAGAAGGCTGCCTTTCCACAGTACCAGCCTGTCGTCATGCTGGAGAAGGGT TATACCATCCACTGGAATGGGCCGGCACCACGGACTACATTTCTATACCTCGTCAACTTC AACAAGAATGACTGGATTCGAGTTGGCCTTTGCTATCCATCAAACACAAGTTTTCAAGTT ACCTTTGGCTATTTGCAGCGGCAGAATGGCTCATTATCCAAAATCGAAGAATATGAGCCT GTGCATTCACTGGAAGAACTGCAAAGAAAGCAATCCGAGAGGAAATTCTATTTTGACTCC AGCACGGGGTTACTGTTTTTGTATCTCAAAGCCAAAAGCCACAGGCATGGCCACAGTTAC TGTTCATCTCAGGGATGTGAAAGAGTCAAGATCCAAGCAGCCACAGACTCAAAGGACATC AGTAACTGCATGGCCAAAGCATACCCACAGTACTACAGAAAGCCGTCAGTGGTCAAGCGG ATGCCGGCCATGCTCACTGGACTCTGTCAAGGCTGTGGCACTCGGCAGGTGGTGTTTACT AGTGATCCTCATAAAAGTTACCTCCCTGTGCAATTCCAGTCACCTGATAAAGCAGAAACC CAGCGTGGAGACCCGTCTGTTATTTCTGTCAATGGCACTGACTTTACCTTCCGAAGTGCA GGCGTCCTCCTCCTTGTTGTGGATCCGTGCAGCGTTCCATTCCGCTTGACGGAAAAAACG GTTTTTCCTCTTGCTGATGTCAGTCGCATTGAAGAGTATTTAAAAACAGGCATCCCTCCA AGGTCCATTGTTCTGTTGAGCACAAGAGGAGAAATAAAGCAGTTAAACATTTCACACTTA CTAGTACCTCTGGGATTAGCCAAACCAGCTCATCTTTATGACAAAGGGAGTACCATATTT TTGGGATTCAGTGGAAACTTTAAACCATCATGGACTAAGCTATTTACCAGTCCTGCTGGA CAGGGCCTTGGGGTGCTTGAACAATTCATACCTTTGCAGCTGGACGAATATGGTTGTCCC AGAGCCACCACTGTCCGCAGAAGAGACCTGGAACTGCTAAAGCAAGCTTCAAAAGCACAT |
| Restriction Sites | Please inquire |
| ACCN | NM_001135820 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001135820.1, NP_001129292.1 |
| RefSeq Size | 6351 bp |
| RefSeq ORF | 3963 bp |
| Locus ID | 23670 |
| UniProt ID | Q9UHN6 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (b) has the same N- and C-termini but is shorter compared to isoform a. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227939 | TMEM2 (Myc-DDK-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 13,210.00 |
|
| RC227939L3 | Lenti-ORF clone of TMEM2 (Myc-DDK-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 15,110.00 |
|
| RC227939L4 | Lenti-ORF clone of TMEM2 (mGFP-tagged)-Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 15,110.00 |
|
| RG227939 | TMEM2 (tGFP-tagged) - Human transmembrane protein 2 (TMEM2), transcript variant 2 |
CNY 11,712.00 |
