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PRAK (MAPKAPK5) (NM_003668) Human Untagged Clone
CAT＃: SC109943
MAPKAPK5 (untagged)-Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1
CNY 2,950.00
Product images
CNY 3,990.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MAPKAP-K5; MK-5; MK5; PRAK |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003668 edited
GCCGAGCCCTTTGCTCCCTCGGCCGCGCGGGGACAGGGCTGCTGAGCAGCCTCCGCCTCT CCCGGCTGTGGGGGCCCCACTGAGTATGTCGGAGGAGAGCGACATGGACAAAGCCATCAA GGAAACTTCCATTTTAGAAGAATACAGTATCAATTGGACTCAGAAGCTGGGAGCTGGAAT TAGTGGTCCAGTTAGAGTCTGTGTAAAGAAATCTACTCAAGAACGGTTTGCGCTGAAAAT TCTTCTTGATCGTCCAAAAGCTAGAAATGAGGTACGTCTGCACATGATGTGTGCCACACA CCCAAACATAGTTCAGATTATTGAAGTGTTTGCTAACAGTGTCCAGTTTCCCCATGAGTC CAGCCCTAGGGCCCGACTCTTAATTGTAATGGAGATGATGGAAGGGGGAGAGCTATTTCA CAGAATCAGCCAGCACCGGCACTTTACAGAGAAGCAAGCCAGCCAAGTAACAAAGCAGAT AGCTTTGGCTCTGCGGCACTGTCACTTGTTAAACATTGCGCACAGAGACCTCAAGCCTGA AAATCTGCTTTTTAAGGATAACTCTTTGGATGCCCCAGTGAAGTTGTGTGACTTTGGATT TGCCAAGATTGACCAAGGTGACTTGATGACACCCCAGTTCACCCCTTATTATGTAGCACC CCAGGTACTGGAGGCGCAAAGAAGGCATCAGAAGGAGAAATCTGGCATCATACCTACCTC ACCGACGCCCTACACTTACAACAAGAGCTGTGACTTGTGGTCCCTAGGGGTGATTATCTA TGTGATGCTGTGCGGATACCCTCCTTTTTACTCCAAACACCACAGCCGGACTATCCCAAA GGATATGCGAAGAAAGATCATGACAGGCAGTTTTGAGTTCCCAGAGGAAGAGTGGAGTCA GATCTCAGAGATGGCCAAAGATGTTGTGAGGAAGCTCCTGAAGGTCAAACCGGAGGAGAG ACTCACCATCGAGGGAGTGCTGGACCACCCCTGGCTCAATTCCACCGAGGCCCTGGATAA TGTGCTGCCTTCTGCTCAGCTGATGATGGACAAGGCAGTGGTTGCAGGAATCCAGCAGGC TCACGCGGAACAGTTGGCCAACATGAGAATCCAGGATCTGAAAGTCAGCCTCAAACCCCT GCACTCAGTGAACAACCCCATTCTGCGGAAGAGGAAGTTACTTGGCACCAAGCCAAAGGA CAGTGTCTATATCCACGACCATGAGAATGGAGCCGAGGATTCCAATGTTGCCTTGGAAAA ACTCCGAGATGTGATTGCTCAGTGTATTCTCCCCCAGGCTGGAGAGAATGAAGATGAGAA ACTGAATGAAGTAATGCAGGAGGCTTGGAAGTATAACCGGGAATGCAAACTCCTAAGAGA TACTCTGCAGAGCTTCAGCTGGAATGGTCGTGGATTCACAGATAAAGTAGATCGACTAAA ACTGGCAGAAATTGTGAAGCAGGTGATAGAAGAGCAAACCACGTCCCACGAATCCCAATA ATGACAGCTTCAGACTTTGTTTTTTTAACAATTTGAAAAATTATTCTTTAATGTATAAAG TAATTTTATGTAAATTAATAAATCATAATTTCATTTCCACATTGATTAAAGCTGCTGTAT AGATTTAGGGTGCAGGACTTAATAATAGTATAGTTATTGTTTGTTTTTAAGAAAAGCTCA GTTCTAGAGACATACTATTACTTTAGGACTGTGTAGTTGTATATTTGTAAGATGACAGAT GATGCTGTCAAGCAATATTGTTTTATTTGTAATAAAATATACAAAAATCACTTGCCAGCA GTAGAAAAAGGACCGACTATACCGACCTTTCTGATTAGTAAACAGTTGAATCAAGGACTC TGGATTCTGGTTTCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003668 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003668.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003668.2, NP_003659.2 |
| RefSeq Size | 2060 bp |
| RefSeq ORF | 1416 bp |
| Locus ID | 8550 |
| UniProt ID | Q8IW41 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | MAPK signaling pathway |
| Gene Summary | The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012] Transcript Variant: This variant (1) is the more frequently occurring transcript. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216715 | MAPKAPK5 (Myc-DDK-tagged)-Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
CNY 3,656.00 |
|
| RC216715L1 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC216715L2 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC216715L3 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC216715L4 | Lenti ORF clone of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG216715 | MAPKAPK5 (tGFP-tagged) - Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
CNY 5,256.00 |
|
| SC323359 | MAPKAPK5 (untagged)-Kinase deficient mutant (K45M) of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1 |
CNY 3,656.00 |
