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PRAK (MAPKAPK5) (NM_003668) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC216715L4V
- LentiORF®
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Lenti ORF particles, MAPKAPK5 (mGFP-tagged) - Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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CNY 3,990.00
Specifications
| Product Data | |
| Product Name | PRAK (MAPKAPK5) (NM_003668) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | MAPKAP-K5; MK-5; MK5; PRAK |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_003668 |
| ORF Size | 1413 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC216715).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_003668.2 |
| RefSeq Size | 2060 bp |
| RefSeq ORF | 1416 bp |
| Locus ID | 8550 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | MAPK signaling pathway |
| MW | 53.9 kDa |
| Gene Summary | The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012] |
Documents
| Product Manuals |
| FAQs |
| SDS |
