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ALDH1L1 (NM_012190) Human Untagged Clone
CAT＃: SC111756
ALDH1L1 (untagged)-Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1)
CNY 6,616.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | 10-fTHF; 10-FTHFDH; FDH; FTHFD |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111756 sequence for NM_012190 edited (data generated by NextGen Sequencing)
ATGAAGATTGCAGTGATTGGACAGAGCCTGTTTGGCCAGGAAGTTTACTGCCACCTGAGG AAGGAGGGCCACGAAGTGGTGGGTGTGTTCACTGTTCCAGACAAGGATGGAAAGGCCGAC CCCCTGGGTCTGGAAGCTGAGAAGGATGGAGTGCCGGTATTCAAGTACTCCCGGTGGCGT GCAAAAGGACAGGCTTTGCCTGATGTGGTGGCAAAATACCAGGCTTTGGGGGCCGAGCTC AACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAGATAATCAGTGCCCCCCGGCAT GGCTCCATCATCTATCACCCGTCACTGCTCCCTAGGCACCGAGGGGCCTCGGCCATCAAC TGGACCCTCATTCACGGAGATAAGAAAGGGGGGTTTTCCATCTTCTGGGCGGATGATGGT CTGGACACCGGAGACCTGCTGCTGCAGAAGGAGTGTGAGGTGCTCCCGGACGACACCGTG AGCACGCTGTACAACCGCTTCCTCTTCCCTGAAGGCATCAAAGGGATGGTGCAGGCCGTG AGGCTGATCGCTGAGGGCAAAGCCCCCAGACTCCCTCAGCCTGAGGAAGGAGCCACCTAT GAGGGGATTCAGAAGAAGGAGACAGCCAAGATCAACTGGGACCAGCCGGCAGAGGCCATT CACAACTGGATCCGCGGGAACGACAAGGTGCCGGGAGCCTGGACAGAGGCCTGTGAACAG AAACTGACATTTTTCAACTCAACGCTGAACACTTCAGGCCTGGTGCCCGAGGGAGACGCT TTGCCCATCCCAGGAGCCCATCGGCCAGGGGTGGTCACCAAAGCAGGACTCATCCTCTTT GGGAATGATGACAAAATGCTGCTGGTGAAGAATATTCAGCTGGAGGATGGCAAAATGATC CTGGCCTCGAACTTCTTTAAGGGGGCAGCCAGCAGTGTCCTTGAGCTGACAGAGGCAGAG CTGGTTACTGCGGAGGCTGTGCGGAGTTTTTGGCAGCGGATCCTCCCCAAAGTCCTGGAG GTTGAAGACTCCACTGATTTCTTCAAGTCAGGGGCCGCGTCTGTGGACGTTGTGAGGCTG GTGGAGGAAGTGAAGGAGCTGTGTGATGGCCTGGAGTTAGAAAATGAAGATGTGTACATG GCATCCACCTTTGGGGACTTCATCCAGCTGTTAGTGAGGAAGCTTCGAGGGCACGATGAG GAGGGCGAGTGCAGCATTGACTACGTGGAAATGGCAGTGAACAAGCGCACTGTCCGCATG CCCCACCAGCTCTTCATTGGGGGGGAGTTCGTGGATGCCGAGGGCGCCAAGACCTCTGAG ACCATCAATCCCACCGATGGAAGTGTCATCTGCCAGGTATCCCTGGCCCAAGTCACCGAC GTCGACAAGGCAGTGGCCGCAGCCAAGGATGCCTTTGAGAATGGACGGTGGGGGAAGATC GGTGCGCGGGACCGGGGCCGGCTGATGTACAGGTTGGCAGATCTCATGGAGCAGCACCAG GAGGAGCTGGCCACCATTGAGGCCCTGGATGCGGGTGCCGTCTACACGCTGGCCCTGAAG ACCCACGTGGGCATGTCCATCCAGACCTTCCGCTACTTTGCTGGCTGGTGTGACAAGATC CAGGGCTCCACCATCCCCATCAACCAGGCCAGACCCAACCGCAACCTGACCTTGACCAGG AAGGAGCCTGTTGGGGTTTGTGGCATCATCATCCCCTGGAACTATCCCCTGATGATGCTG TCCTGGAAGACAGCTGCCTGCCTGGCTGCCGGGAACACAGTGGTGATCAAGCCTGCTCAG GTGACCCCACTCACAGCCTTGAAGTTTGCAGAGCTGACATTAAAGGCCGGCATTCCCAAA GGTGTGGTTAACGTCCTCCCAGGATCTGGCTCCCTGGTCGGCCAGAGACTCTCAGACCAT CCTGATGTGAGGAAAATCGGGTTCACAGGCTCCACAGAGGTGGGCAAGCACATCATGAAA AGCTGTGCCATAAGTAACGTGAAGAAGGTGTCCCTGGAACTGGGCGGGAAGTCACCCCTC ATCATCTTTGCTGACTGTGACCTCAACAAGGCTGTGCAGATGGGGATGAGTTCTGTTTTC TTCAACAAAGGAGAGAATTGCATTGCAGCAGGCCGACTCTTTGTGGAGGACTCCATTCAT GATGAGTTCGTGCGGAGAGTGGTAGAAGAGGTGCGGAAGATGAAGGTGGGCAACCCGCTG GACAGGGACACCGACCACGGGCCGCAGAATCACCATGCCCACCTTGTGAAGCTGATGGAG TACTGCCAGCATGGCGTGAAGGAAGGGGCCACACTGGTCTGCGGCGGGAATCAGGTCCCT CGGCCAGGGTTCTTCTTTGAGCCAACTGTTTTCACAGACGTGGAAGACCACATGTTCATA GCCAAGGAGGAGTCCTTCGGGCCTGTCATGATCATCTCTCGGTTTGCTGATGGGGACTTG GATGCCGTGCTGTCTCGGGCCAATGCCACGGAATTTGGCCTGGCTTCTGGTGTCTTCACC AGGGACATCAACAAGGCCCTGTATGTCAGTGACAAGCTCCAGGCAGGCACTGTGTTTGTC AACACGTACAACAAGACCGACGTGGCCGCTCCCTTCGGAGGATTCAAACAGTCTGGATTT GGCAAAGATCTAGGAGAGGCGGCTCTGAACGAGTACCTGCGGGTCAAGACAGTGACCTTC GAATACTGA Clone variation with respect to NM_012190.2 988 g=>t;1185 g=>t;1192 g=>c;1441 a=>g >OriGene 5' read for NM_012190 unedited
TTCGGNCCTCAGCTGCGGCTCATTTAAGTCTAACCTGCCCGGGACGCCCGCACCAACTCC TGCGCGCGGTCCTTCCAACCCTCCTGCTACCATGAAGATGCAGTGATTGGACAACCTGTT TGGCCAGAATTTACTGCCACCTGAGAAGAGGCCACGAATGTNGGGTAGNTCACTGTTCCA TACAAGGATTGAAAGGCCGACCCCCTGGGTCTGGAAGCTGAGAAGGATGGAGTGCCGGTA TTCAAGTACTCCCTGTGGCGTGCAAAAGGACAGGCTTTGCCTGATGTGGTGGCAAAATAC CAGGCTTTGGGGGCCGAGCTCAACGTCCTGCCCTTCTGCAGCCAATTCATCCCCATGGAG ATAATCAGTGCCCCCCGGCATGGCTCCATCATCTATCACCCGTCACTGCTCCCTAGGCAC CGAGGGGCCTCGGCCATCAACTGGACCCTCATTCACGGAGATAAGAAAGGGGGGTTTTCC ATCTTCTGGGCGGATGATGGTCTGGACACCGGAGACCTGCTGCTGCAGAAAGAGTGTGAG GTGCTCCCGGACGACACCGTGAGCACGCTGTACAACCGCTTCCTCTTCCCTGAGGCATCA AAGGGATGGTGCAGGCCGTGAGGCTGATCCCTGANGCAAAACCCCCAAACTCCCTCACCC TGAGGAAGGAACACCTATGAGGGGATTCAGAAAAAGGAGAACGCCAGAATCACTTGGGAC CAGCCCGGCAGAGCCATTTCCAACTTGGATCCGGGGGAACAAACAAGTGCCCGGGAGCCT GGGCAAAAGGCCTGTTGAACAGAAACTGGAATTNTTTCAACTTAACGCCTTGAACATTCA AGGCCTGGGCCCCCGAGGGAAACCCTTTGCCCATCCCAGGAACCCCTCCGCCCCAGGGTG GTC >OriGene 3' read for NM_012190 unedited
ACTCTGGACCGCGGCNCGCAATCTANGATNCGGTTTTTTTTTTTTTTTTTTTTTTTTTCT CTTCATAAGCTTTATTCTCCCTGGGAGGGGCACACCTCACCCAGCCAAGGGCTGCTTCTG ACTGGACAGAGGGCGTCCAAAATGCAAACATGGTGTGCAGGCAGGAGGGCTTCCACTAGC CCCCCAGGTGGGAGGTGCTGTGCACCCAGGCTCAAGAGGGAGGGGGCCCCAGCCACGAGG GAGGGGCAGGGACTTTCTTCTCACAAAGACCTTTCTTCAGTATTCGAAGGTCACTGTCTT GACCCGCAGGTACTCGTTCAAAGCCGCCTCTCCTAAATCTTTGCCAAATCCAGACTGTTT GAATCCTCCGAAGGGAGCGGCCACGTCGGTCTTGTTGTACGTGTTGACAAACACAGTGCC TGCCTGGAGCTTGTCACTGACATACAGGGCCTTGTTGATGTCCCTGGTGAAGACACCAGA AGCCAGGCCAAATTCCGTGGCATTGGCCCGAGACAGCACGGCATCCAAGTCCCCATCAGC AAACCGAGAGATGATCATGACAGGCCCGAAGGACTCCTCCTTGGCTATGAACATGTGGTC TTCCACGTCTGTGAAAACAGTTGGCTCAAAGAAGAACCCTGGCCGAGGGACCTGATTCCC GCCGCAGACCAGTGTGGCCCCTTCCTTCACGCCATGCTGGCAGTACTCCATCAGCTTCAC AAGGTGGGCATGGTGATTCTGCGGCCCCGTGGTCGGTGTCCCTGTCCAGCGGGGTGCCCA CCTTCATCTTCCGCACCTTTNTACCACTCTNCGCACGAACNATCATGAATGGAGTCCTNC ACAAAGAGTCGCCTGCTGCATGCAATCTCTCCTTTGTTGAAGAAACAGACTCATCCCATC TGCACANCTTGGTGAGTCACAGTCAGCAAAATGATGAGGGTGACTTCCCGCCCAGTCAGG GACACTTCTNACAGTACTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012190 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_012190.2, NP_036322.2 |
| RefSeq Size | 3125 bp |
| RefSeq ORF | 2709 bp |
| Locus ID | 10840 |
| UniProt ID | O75891 |
| Domains | aldedh, formyl_transf, formyl_trans_C |
| Protein Families | Druggable Genome |
| Protein Pathways | One carbon pool by folate |
| Gene Summary | The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] Transcript Variant: This variant (2) contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region, and initiates translation at an alternate in-frame downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213720 | ALDH1L1 (Myc-DDK-tagged)-Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1) |
CNY 6,608.00 |
|
| RC213720L3 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC213720L4 | Lenti ORF clone of Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1), mGFP tagged |
CNY 9,030.00 |
|
| RG213720 | ALDH1L1 (tGFP-tagged) - Human aldehyde dehydrogenase 1 family, member L1 (ALDH1L1) |
CNY 8,208.00 |
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