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SCUBE2 (NM_020974) Human Untagged Clone
CAT＃: SC113056
SCUBE2 (untagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1
CNY 7,320.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CEGB1; CEGF1; CEGP1; scube/You |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC113056 sequence for NM_020974 edited (data generated by NextGen Sequencing)
ATGGGGGTCGCGGGCCGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGCTGCTG CTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGGGCCGTGCCGCG GGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCGACGCC CTGTGTCAGAACACACCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAGGGGAA GGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGGAGGCTGTGTCCAT GACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGTTGGCT CATGACGGTCATAATTGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCTGCCAG CATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGGGGTTTTTCCTG AGTGACAATCAGCACACCTGCATTCACCGCTCGGAAGAGGGCCTGAGCTGCATGAATAAG GATCACGGCTGTAGTCACATCTGCAAGGAGGCCCCAAGGGGCAGCGTCGCCTGTGAGTGC AGGCCTGGTTTTGAGCTGGCCAAGAACCAGAGAGACTGCATCTTGACCTGTAACCATGGG AACGGTGGGTGCCAGCACTCCTGTGACGATACAGCCGATGGCCCAGAGTGCAGCTGCCAT CCACAGTACAAGATGCACACAGATGGGAGGAGCTGCCTTGAGCGAGAGGACACTGTCCTG GAGGTGACAGAGAGCAACACCACATCAGTGGTGGATGGGGATAAACGGGTGAAACGGCGG CTGCTCATGGAAACGTGTGCTGTCAACAATGGAGGCTGTGACCGCACCTGTAAGGATACT TCGACAGGTGTCCACTGCAGTTGTCCTGTTGGATTCACTCTCCAGTTGGATGGGAAGACA TGTAAAGATATTGATGAGTGCCAGACCCGCAATGGAGGTTGTGATCATTTCTGCAAAAAC ATCGTGGGCAGTTTTGACTGCGGCTGCAAGAAAGGATTTAAATTATTAACAGATGAGAAG TCTTGCCAAGATGTGGATGAGTGCTCTTTGGATAGGACCTGTGACCACAGCTGCATCAAC CACCCTGGCACATTTGCTTGTGCTTGCAACCGAGGGTACACCCTGTATGGCTTCACCCAC TGTGGAGACACCAATGAGTGCAGCATCAACAACGGAGGCTGTCAGCAGGTCTGTGTGAAC ACAGTGGGCAGCTATGAATGCCAGTGCCACCCTGGGTACAAGCTCCACTGGAATAAAAAA GACTGTGTGGAAGTGAAGGGGCTCCTGCCCACAAGTGTGTCACCCCGTGTGTCCCTGCAC TGCGGTAAGAGTGGTGGAGGAGACGGGTGCTTCCTCAGATGTCACTCTGGCATTCACCTC TCTTCAGGACTGCAAGGGGCCTACTCTGTCACCTGTGGCTCTTCCTCTCCTCTCAGGAAC AAACAACAAAAATCAAATGACTCTGCTTTTGGGGATGTCACCACCATCAGGACAAGTGTA ACCTTTAAGCTAAATGAAGGCAAGTGTAGTTTGAAAAATGCTGAGCTGTTTCCCGAGGGT CTGCGACCAGCACTACCAGAGAAGCACAGCTCAGTAAAAGAGAGCTTCCGCTACGTAAAC CTTACATGCAGCTCTGGCAAGCAAGTCCCAGGAGCCCCTGGCCGACCAAGCACCCCTAAG GAAATGTTTATCACTGTTGAGTTTGAGCTTGAAACTAACCAAAAGGAGGTGACAGCTTCT TGTGACCTGAGCTGCATCGTAAAGCGAACCGAGAAGCGGCTCCGTAAAGCCATCCGCACG CTCAGAAAGGCCGTCCACAGGGAGCAGTTTCACCTCCAGCTCTCAGGCATGAACCTCGAC GTGGCTAAAAAGCCTCCCAGAACATCTGAACGCCAGGCAGAGTCCTGTGGAGTGGGCCAG GGTCATGCAGAAAACCAATGTGGTCTGTGTCAACCTGGTGAATATTCTGCAGATGGCTTT GCACCTTGCCAGCTCTGTGCCCTGGGCACGTTCCAGCCTGAAGCTGGTCGAACTTCCTGC TTCCCCTGTGGAGGAGGCCTTGCCACCAAACATCAGGGAGCTACTTCCTTTCAGGACTGT GAAACCAGAGTTCAATGTTCACCTGGACATTTCTACAACACCACCACTCACCGATGTATT CGTTGCCCAGTGGGAACATACCAGCCTGAATTTGGAAAAAATAATTGTGTTTCTTGCCCA GGAAATACTACGACTGACTTTGATGGCTCCACAAACATAACCCAGTGTAAAAACAGAAGA TGTGGAGGGGAGCTGGGAGATTTCACTGGGTACATTGAATCCCCAAACTACCCAGGCAAT TACCCAGCCAACACCGAGTGTACGTGGACCATCAACCCACCCCCCAAGCGCCGCATCCTG ATCGTGGTCCCTGAGATCTTCCTGCCCATAGAGGACGACTGTGGGGACTATCTGGTGATG CGGAAAACCTCTTCATCCAATTCTGTGACAACATATGAAACCTGCCAGACCTACGAACGC CCCATCGCCTTCACCTCCAGGTCAAAGAAGCTGTGGATTCAGTTCAAGTCCAATGAAGGG AACAGCGCTAGAGGGTTCCAGGTCCCATACGTGACATATGATGAGGACTACCAGGAACTC ATTGAAGACATAGTTCGAGATGGCAGGCTCTATGCATCTGAGAACCATCAGGAAATACTT AAGGATAAGAAACTTATCAAGGCTCTGTTTGATGTCCTGGCCCATCCCCAGAACTATTTC AAGTACACAGCCCAGGAGTCCCGAGAGATGTTTCCAAGATCGTTCATCCGATTGCTACGT TCCAAAGTGTCCAGGTTTTTGAGACCTTACAAATGA Clone variation with respect to NM_020974.2 >OriGene 5' read for NM_020974 unedited
GGATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATCGGCACGAGGCCGCGCACAC CTCCCCGCGCCGCCGCCGCCACCGCCCGCACTCCGCCGCCTCTGCCCGCAACCGCTGAGC CATCCATGGGGGTCGCGGGCCGCAACCGTCCCGGGGCGGCCTGGGCGGTGCTGCTGCTGC TGCTGCTGCTGCCGCCACTGCTGCTGCTGGCGGGGGCCGTCCCGCCGGGTCGGGGCCGTG CCGCGGGGCCGCAGGAGGATGTAGATGAGTGTGCCCAAGGGCTAGATGACTGCCATGCCG ACGCCCTGTGTCAGAACACACCCACCTCCTACAAGTGCTCCTGCAAGCCTGGCTACCAAG GGGAAGGCAGGCAGTGTGAGGACATCGATGAATGTGGAAATGAGCTCAATGGAGGCTGTG TCCATGACTGTTTGAATATTCCAGGCAATTATCGTTGCACTTGTTTTGATGGCTTCATGT TGGCTCATGACGGTCATAATTGTCTTGATGTGGACGAGTGCCTGGAGAACAATGGCGGCT GCCAGCATACCTGTGTCAACGTCATGGGGAGCTATGAGTGCTGCTGCAAGGAGGGGTTTT TCCTGAGTGACAATCAGCACACCTGCATTCACCGCTNCGAAGAGGCCTGAGCTGCATGAA TAAGGATCACGGCTGTAGTCACATCTGCAAGGANGGCCCCAAGGNGCAGCGTCGCCTGTG AGTGCANGCCTGGNTTTGAGCTGCCCAGAACAGAGAGACTGCATCTTGACCTGTAACCAT GGGAACGGTGGNTGCCAGCACTNCTGTGACATACAGCCGATGGCCCAGATGCAGCTGCCA TCCCAGTACAGGATGCACACGATGGGGAGAGCTGGCTTGACGAGAAGACACTGTCCTGNN AGTGACGAAAAGCACACCCATCAATGGTGGATGGGATAACGGGTGAAACGCGCTGTCATG AACCNTGGCTGCACAATGAGCT >OriGene 3' read for NM_020974 unedited
AGCTATGCCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCAATTTACCA AAATATCTGTATTATCTATAAAAATTGAACTCTAATGAGTCACTGATACGGGAGGCAGCA ATACCCGACTGTGCTGACATGCAGAAGGAAGACAGCTCTGTCCCACCAACCCTATAGCAG AACATTTGTATTGAGTGGCACGTGGGCTGAGTCATTTGTAAGGTCTCAAAAACCTGGACA CTTTGGAACGTAGCAATCGGATGAACGATCTTGGAAACATCTCTCGGGACTCCTGGGCTG TGTACTTGAAATAGTTCTGGGGATGGGCCAGGACATCAAACAGAGCCTTGATAAGTTTCT TATCCTTAAGTATTTCCTGATGGTTCTCAGATGCATAGAGCCTGCCATCTCGAACTATGT CTTCAATGAGTTCCTGGTAGTCCTCATCATATGTCACGTATGGGACCTGGAACCCTCTAG CGCTGTTCCCTTCATTGGACTTGAACTGAATCCACAGCTTCTTTGACCTGGAGGTGAAGG CGATGGGGCGTTCGTAGGTCTGGCAGGTTTCATATGTTGTCACAGAATTGGATGAAGAGG TTTTCCGCATCACCAGATAGTCCCCACAGTCGTCCTCTATGGGCAGGAAGATCTCANGGA CCACGATCAGGATGCGGCGCTTGGGGGGTGGGTTGATGGTCCACGTACACCNTCGTGNTG GCTGGGNTAATTGCCTGGGGTAGTTGGGGGGATTCAATGTACCCAGTGAAAATCTCCAGC TNCCCTNCACATCNTCTGTTTTTACACTGGGGGTATGTTGTGGGAGCCATCAAAGTCAGT CGTAGTATTTCCTGGGCAAGAAACACATTATTTTTTCCAAATCAGGGCTGTATGTTTCCA CTGGGCAACGAATACATCGTGANTGGGGGTGTTGTAAAATGTTCAGNGAACATTGACCTT GGGTTCA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_020974 |
| Insert Size | 3850 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020974.1, NP_066025.1 |
| RefSeq Size | 3737 bp |
| RefSeq ORF | 3000 bp |
| Locus ID | 57758 |
| UniProt ID | Q9NQ36 |
| Domains | CUB, EGF_CA, EGF, EGF |
| Protein Families | Transmembrane |
| Gene Summary | Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224136 | SCUBE2 (Myc-DDK-tagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1 |
CNY 9,790.00 |
|
| RC224136L3 | Lenti-ORF clone of SCUBE2 (Myc-DDK-tagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1 |
CNY 11,690.00 |
|
| RC224136L4 | Lenti-ORF clone of SCUBE2 (mGFP-tagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1 |
CNY 11,690.00 |
|
| RG224136 | SCUBE2 (tGFP-tagged) - Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1 |
CNY 9,648.00 |
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