SCUBE2 (NM_020974) Human Tagged ORF Clone Lentiviral Particle

CAT＃: RC224136L4V

  • LentiORF®

Lenti ORF particles, SCUBE2 (mGFP-tagged)-Human signal peptide, CUB domain, EGF-like 2 (SCUBE2), transcript variant 1, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet
SDS

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CNY 19,000.00

货期*
详询
规格
    • 200 ul

Product images

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Specifications

Product Data
Product Name SCUBE2 (NM_020974) Human Tagged ORF Clone Lentiviral Particle
Synonyms CEGB1; CEGF1; CEGP1; scube/You
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_020974
ORF Size 2997 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC224136).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_020974.1, NP_066025.1
RefSeq Size 3737 bp
RefSeq ORF 2916 bp
Locus ID 57758
Domains CUB, EGF_CA, EGF, EGF
Protein Families Transmembrane
MW 106.6 kDa
Gene Summary Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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