KREMEN2 (NM_024507) Human Untagged Clone

CAT#: SC127217

KREMEN2 (untagged)-Human kringle containing transmembrane protein 2 (KREMEN2), transcript variant 2



  "NM_024507" in other vectors (6)

CNY 7,220.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal KREMEN2 Antibody
    • 100 ug

CNY 5,808.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms KRM2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_024507, the custom clone sequence may differ by one or more nucleotides


ATGGGGACACAAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCT
CGGCTGGGAGCCTGCACAGTCCAGGCCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACTACCGCGGCCA
CCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGGACCAGACGCAGCAACACAGC
TACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGGGCGCGCACAACTTCTGCCGTAACCCAGACG
GTGACGTGCAGCCGTGGTGCTACGTGGCTGAGACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCC
CTCCTGTCACATGCCAGGCTACCTGGGATGCTTTGTGGACTCAGGGGCACCCCCAGCCCTCAGCGGCCCC
AGCGGCACCTCCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTGG
CGGGCGTGGAGGCCGGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCGGGGACGCCTGGCCCC
CGCCACCGACTGTGACCAGATCTGTTTCGGCCACCCTGGACAGCTGTGTGGCGGCGATGGGCGGCTGGGC
GTCTATGAAGTGTCGGTGGGCTCCTGCCAGGGGAACTGGACAGCGCCTCAGGGCGTCATCTACTCCCCGG
ACTTCCCGGACGAGTACGGGCCGGACCGGAACTGCAGCTGGGCCCTGGGCCCGCCAGGCGCCGCGCTGGA
GCTCACCTTCCGCCTCTTCGAGCTGGCCGACCCGCGCGACCGGCTGGAGCTGCGCGACGCGGCTTCGGGC
AGCCTGCTCCGCGCCTTCGATGGCGCCCGCCCACCGCCGTCCGGGCCGCTGCGCCTGGGCACTGCCGCGC
TGCTGCTCACCTTCCGAAGCGACGCGCGCGGCCACGCGCAAGGCTTCGCGCTCACCTACCGCGGGCTGCA
GGACGCCGCTGAGGACCCAGAGGCCCCCGAGGGCTCGGCCCAGACCCCCGCGGCGCCCCTCGACGGGGCC
AACGTGAGCTGCAGCCCCAGGCCTGGGGCTCCGCCGGCCGCGATTGGGGGAGCTGTCTGCTGGCTCCGGG
AAAAGGGCCCCCGGCGCTGGGGGCTTCCAGGGGCCCCAGGAGAAGCTGGGCTGTGTGGTACCAACAGCCC
CGAGGGGTGGCCTTGCCCTGCTCCCCCGGGGACCCCCAGGCTGAGGGTTCTGCCGCGGGCTACCGGCCTC
TGA


>OriGene 5' read for NM_024507 unedited
NAAAACATTTCACATTTGTATACGACTCATATAGGCGGCACGCGAATTCGCACGAGGGGG
TATACTGTCAGAGGACAACGCCCCCTAGGTCTCCTGGGAGACCCCGAAGCGACCCCGGGG
GCAGCCCGGGCCGTGTCCGGGCGAGGGTGACCTATCCTTGGTTGAGAGCGATGGGGACAC
AAGCCCTGCAGGGCTTCCTCTTTCTCCTCTTCCTCCCGCTGCTGCAGCCGCGTGGGGCCT
CGGCTGGGAGCCTGCACAGTCCAGGCCTGTCCGAATGCTTCCAGGTGAATGGGGCTGACT
ACCGCGGCCACCAGAACCGCACTGGCCCGCGCGGGGCGGGCCGCCCGTGCCTCTTCTGGG
ACCAGACGCAGCAACACAGCTACAGCAGCGCCAGCGACCCCCACGGCCGCTGGGGGCTGG
GCGCGCACAACTTCTGCCGTAACCCAGACGGTGACGTGCAGCCGTGGTGCTACGTGGCTG
ATACAGAGGAGGGCATCTACTGGCGCTACTGCGACATCCCCTCCTGTCACATGCCAGGCT
ACCTGGGATGCTTTGTGGACTCAGGGGCACCCCCAGCCCTCAGCGGCCCCAGCGGCACCT
CCACGAAGCTCACGGTCCAGGTGTGCCTACGCTTCTGCCGCATGAAGGGGTACCAGCTTG
GCGGGCGTGGAGGCCCGTTACGCCTGCTTCTGTGGCTCTGAAAGCGACCTGGCCCCGGTG
ACCCCTGGGCCCCGCCACCGAATGGGACCAGATCTGTTTCGGCCACNCTGGGAAGCTGTG
TGGCGGCCATGGGCGGCTGGGCGTCTATGAAGGTGCGTGGGCTCCTGCCAGGGGAACTGG
ACAGCGCCTCATGGGGTCATCTACTCT
>OriGene 3' read for NM_024507 unedited
GACCTTTGGCGATGTGCACTTCCCAGTTCCAGNANAGCACTGGGGCAGGGTCACAGGCAT
GCCACCCGGGTATCTGTTGCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAG
TTTTTTTTTTTTTTTTTTACCAAAGTAGATCCTTTATTCAAAATCTGTGGGGGTTTTTTG
ACTGTTTTTGCTGACCTGTGACCTCTCACTGAGGACGGCAGTCCAGGACCACCCCCAGAG
GGGTTCAAAGACCTCCGAAACCAGAGACCACCCCCACATACAGGTCCATGGAGAGGGCCT
GGACCATCTGGACCCCCACGGTCAGGCCAAGTCCCAGATAATAGCACCAGATGTTTCCTG
TCCGACTTTTGGTCTCCCCAAGGCGACCAGAGGCCGAGCTGCCCCTACACAGGCGCAAGG
CCGAGGCAGGGCGCAGCACAGCATCTCAGGTGTCCATCTCGCCGGCGGCGGGCCCAGCGG
ACCCTCGGGGCCCAGAGTCAGAGAGCGGATATGAGCGAGCGCAGGGAGCTCTGGCTGGAG
GCACTCAGAGGCCGGTAGCCCGCGGCAGAACCCTCAGCCTGGGGGTCCCCGGGGGAGCAG
GGCAAGGCCACCCCTCGGGGCTGTTGGTACCACACAGCCCATCTTCTCCTGGGGCCCCTG
GAAGCCCCCAGCGCCGGGGGCCCTTTTCCCGGAGCCAGCAGACAGCTCCCCCAATCGCGG
CCGGCGGAGCCCCAGCCTGGGGCTGCAGCTCACGTTGGCCCCGTCGAGGGGCGCCGCGGG
GGTCTGGGCCGAGCCCTCGGGGGCCTCTGGGTCCTCAGCGGCGTCCTGCAACCCGCGTAG
GTGAGCGCAAGCCCTGCGCGTGGCCCGCGCGTCGCTCGGAGGTGAGCAGCACGCGGAGTG
CCCAGCGCAGCGCCCN
Restriction Sites Please inquire     
ACCN NM_024507
Insert Size 2000 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_024507.2, NP_078783.1
RefSeq Size 1992 bp
RefSeq ORF 1263 bp
Locus ID 79412
UniProt ID Q8NCW0
Protein Families Druggable Genome, Transmembrane
Gene Summary This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Transcript Variant: This variant (2), also called kremen2b, lacks an exon in the 3' coding region compared to variant 4, resulting in a frameshift. The encoded isoform (b) is shorter and has a distinct C-terminus compared to isoform d.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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