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AKNA (NM_030767) Human Untagged Clone
CAT＃: SC311505
AKNA (untagged)-Human AT-hook transcription factor (AKNA)
CNY 9,856.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_030767 edited
GTCAGAAGGAAGCACCACACAGAGGGCACAGGCAGGATGGCCGATGCTGACAGGAACCAG CGGTGACTCTGGGGCCCCTGGCAGCAGCTCTGTCTCCTGAAGATGAAGTGGCCCAGGTGA AGCCCAGGCCAGCCCCAATGGCCAGCTCGGAGACTGAGATCCGCTGGGCTGAGCCTGGCC TGGGGAAGGGCCCCCAGCGGCGGCGCTGGGCCTGGGCCGAGGACAAGAGGGATGTGGATA GAAGTAGTTCACAAAGCTGGGAAGAAGAGAGACTCTTTCCCAATGCCACCAGCCCCGAGC TCCTAGAGGACTTCCGCCTGGCCCAGCAGCACCTGCCGCCCCTGGAGTGGGACCCACACC CGCAGCCCGATGGGCATCAGGATTCCGAGTCAGGAGAGACTTCGGGAGAAGAGGCTGAAG CAGAGGATGTGGACAGCCCAGCAAGTTCCCATGAGCCTCTTGCCTGGCTCCCCCAGCAGG GCCGTCAGCTGGACATGACTGAAGAGGAGCCAGATGGGACCCTCGGAAGTCTGGAGGTTG AGGAGGCTGGAGAGAGCTCCTCAAGGTTGGGGTATGAGGCTGGTCTCAGCTTGGAAGGCC ATGGAAACACCAGCCCCATGGCTCTTGGGCATGGTCAGGCCAGGGGCTGGGTGGCTTCTG GCGAACAAGCCAGTGGGGACAAACTTTCTGAACATTCCGAGGTCAACCCATCCGTTGAAC TCAGCCCGGCAAGGTCCTGGAGCAGTGGGACAGTGAGCCTCGACCACCCTAGTGACAGCC TTGATTCTACCTGGGAAGGAGAGACCGATGGCCCCCAGCCCACTGCCCTGGCAGAAACCT TGCCAGAGGGCCCCAGCCACCACCTCCTAAGCCCAGATGGCAGAACTGGAGGCAGTGTTG CTCGGGCAACCCCCATGGAATTCCAGGACTCCTCAGCTCCCCCAGCCCAGAGTCCGCAGC ATGCCACAGATAGATGGAGGAGAGAAACGACCAGATTCTTCTGCCCTCAGCCCAAGGAAC ACATCTGGAAGCAGACAAAGACGTCACCTAAGCCACTCCCTTCCCGATTCATTGGCTCCA TCAGCCCCCTGAATCCCCAGCCCAGGCCAACGCGGCAGGGCAGGCCGCTGCCCAGACAGG GAGCCACTCTGGCTGGCCGCTCCTCTTCTAATGCCCCCAAGTATGGCCGGGGGCAGTTGA ACTACCCACTCCCTGATTTCTCCAAGGTAGGGCCCCGGGTGAGATTCCCCAAAGATGAGA GCTACCGTCCCCCCAAGTCCAGAAGCCACAACAGGAAGCCTCAGGCCCCTGCCAGGCCCC TCATCTTCAAGTCTCCAGCTGAGATTGTGCAGGAGGTGCTGTTGAGCAGTGGAGAAGCAG CCCTGGCAAAGGACACGCCTCCTGCCCACCCTATCACCAGGGTACCCCAAGAATTTCAGA CGCCTGAGCAAGCCACTGAGCTGGTCCATCAGCTCCAGGAAGACTACCACAGGCTCCTCA CCAAGTACGCTGAGGCCGAGAACACCATTGACCAGCTACGCCTCGGGGCCAAGGTGAACC TGTTCTCTGACCCACCCCAGCCCAACCACAGCATCCACACGGGAATGGTGCCCCAGGGGA CCAAGGTCTTGTCCTTCACCATCCCACAGCCCCGCTCTGCAGAGTGGTGGCCGGGCCCGG CCGAGGACCCCCAGGCCTCTGCGGCCTCAGGGTGGCCATCAGCTCGAGGAGACTTGAGCC CCTCCTCGCTTACCAGCATGCCCACCCTGGGGTGGCTTCCGGAGAACCGGGACATCTCTG AGGACCAGTCCTCAGCAGAGCAGACCCAGGCACTGGCTTCTCAGGCCAGCCAGTTCCTGG CCAAGGTGGAGTCCTTTGAAAGACTGATACAGGCAGGACGTCTCATGCCCCAGGACCAAG TCAAGGGCTTCCAGCGGCTGAAGGCTGCCCACGTGGCCCTAGAGGAGGAGTACCTGAAGG CTTGTCGGGAGCAACACCCTGCCCAGCTGCTTGCCGGCTCCAAGGGGACGCCTGGAAGAT TTGATCCTCGCAGGGAGCTGGAGGCAGAGATATACCGTCTGGGAAGCTGCCTGGAAGAGC TGAAGGAACACATAGACCAGACCCAGCAAGAGCCTGAGCCGCCCGGGTCAGACTCAGCTC TGGACAGCACCCCAGCCCTGCCCTGCCTCCATCAGCCAACGCACCTGCCTGCTCCTTCTG GACAAGCCCCCATGCCAGCCATCAAGACCTCCTGCCCTGAGCCTGCTACCACCACTGCCG CCGCCAGCACTGGCCCCTGCCCATTGCACGTAAATGTGGAGGTGAGCTCTGGCAACAGTG AGGTGGAGGACAGGCCACAGGACCCCCTGGCCCGACTCAGGCACAAGGAGCTGCAGATGG AACAAGTTTACCATGGCCTCATGGAGCGGTACCTCAGTGTGAAGTCTCTCCCAGAAGCCA TGAGAATGGAGGAGGAGGAAGAAGGAGAGGAGGAGGAGGAGGAAGAGGGGGGAGGTGACT CCCTGGAAGTTGATGGGGTGGCTGCAACTCCAGGGAAAGCAGAGGCCACCAGGGTCCTCC CAAGGCAGTGCCCGGTGCAGGCTGAGAAAAGTCATGGGGCTCCCCTGGAGGAGGCCACGG AGAAGATGGTATCTATGAAGCCACCAGGTTTCCAGGCATCCCTGGCTAGAGACGGGCACA TGTCAGGCCTGGGCAAGGCTGAGGCAGCCCCTCCAGGCCCTGGCGTGCCACCCCACCCTC CAGGCACCAAGTCCGCAGCATCCCACCAAAGTAGTATGACCAGCCTGGAGGGAAGCGGCA TCTCTGAGCGCCTTCCACAGAAGCCTTTGCACCGAGGCGGTGGGCCCCACCTGGAGGAGA CCTGGATGGCGTCCCCAGAGACAGACAGTGGCTTTGTGGGCTCAGAAACAAGCAGAGTTT CACCCCTCACCCAGACTCCAGAGCACCGGCTCTCCCACATCAGCACAGCAGGAACATTAG CCCAGCCCTTTGCTGCATCTGTGCCCAGGGATGGAGCTTCCTACCCCAAGGCCAGGGGTT CTCTGATTCCCAGAAGAGCCACAGAGCCCAGCACACCCCGGAGCCAAGCACAGAGGTACC TCTCCAGCCCAAGTGGGCCTCTCCGGCAGAGGGCACCCAACTTCAGCCTGGAGCGGACAC TGGCAGCCGAGATGGCGGTTCCTGGCTCAGAGTTTGAGGGGCACAAACGGATTTCTGAAC AGCCCCTTCCCAACAAGACAATCAGCCCACCCCCAGCCCCCGCCCCTGCCGCTGCGCCTC TACCCTGTGGACCAACAGAGACCATCCCCAGCTTCCTGCTCACCAGGGCAGGGCGAGACC AGGCCATCTGTGAGCTGCAAGAAGAGGTGTCCCGGCTTCGTCTGCGGCTGGAAGACAGCC TGCACCAGCCACTCCAGGGCAGCCCGACACGCCCAGCATCTGCCTTTGACCGCCCCGCCC GGACCCGCGGCCGGCCAGCAGACTCCCCAGCCACCTGGGGCTCCCATTATGGCAGTAAAT CCACAGAGAGATTGCCTGGTGAGCCTAGAGGTGAAGAGCAGATTGTCCCTCCAGGAAGGC AGCGAGCCAGGTCTTCCTCAGTGCCTCGGGAGGTGCTCCGACTGTCCCTGAGTTCAGAAT CTGAGCTGCCCTCCCTACCACTGTTCTCTGAGAAGAGCAAGACCACCAAGGACAGTCCAC AGGCAGCTCGGGATGGAAAGAGAGGGGTGGGCAGTGCTGGATGGCCAGACAGGGTCACCT TCCGGGGCCAATACACAGGCCACGAATACCATGTTCTGTCCCCTAAGGCGGTCCCAAAAG GCAATGGCACAGTCTCCTGTCCCCACTGCCGGCCCATTAGGACCCAGGATGCGGGTGGTG CTGTCACAGGGGACCCACTGGGACCGCCTCCCGCTGATACCCTTCAGTGTCCCCTGTGTG GTCAAGTTGGGTCTCCCCCAGAGGCAGATGGTCCAGGCTCAGCCACCTCTGGGGCAGAGA AGGCCACCACGAGGAGAAAAGCACCTTCAACTCCCAGCCCCAAGCAGAGGAGCAAGCAGG CGGGGTCGTCGCCACGCCCACCCCCCGGACTGTGGTATCTGGCAACAGCGCCCCCAGCAC CAGCCCCTCCAGCCTTTGCCTACATCTCCTCGGTTCCCATCATGCCTTATCCACCTGCCG CTGTGTACTATGCGCCTGCAGGACCTACCTCAGCCCAACCAGCTGCCAAGTGGCCGCCCA CAGCCTCTCCCCCACCAGCCCGGAGACACCGGCACTCCATCCAGCTCGACCTGGGCGACC TAGAGGAGCTCAACAAGGCCCTGAGCCGGGCCGTGCAGGCTGCCGAGAGCGTCCGCTCTA CCACCAGGCAGATGAGAAGCTCGCTGTCAGCCGACCTGCGCCAGGCTCACAGCCTGCGGG GCTCCTGCCTCTTCTGACTTCACTGGGGGCCCAGAGGCAGATGGGTGGGTGGGTGGGCAG GTGGCCTGCCAGGCCAGGAGTGGGCTGGAGCTGCTGAGGCCCAGAAGGCCCGCATAGTTC CTCACCAGGAGGGTCTCCCTCCAGCACAGGTCCCGCCTGCTCAGTCCCTGTGCTTTCCAA GTGGAGGGGGTGTCAGCTCGGTCACCAAGAGAAGTGACTTCCCAGGAGCACCAGTCCCCT CACAGAGGTGCTGTGAGCGAGGCCTCCTTCGGTCCAGGCAGAACCTCAGGCAGTCTCTCC TGGTCCTGCATGTGTGCAACTCCAGCTAATAATAGGTATTTTATATACAGATGGACAGAT ATTTTTTTAAACTGGGGAGTTTTCCTGATCTTGGGTCCTCTTTAGGGGGCCAGACAAGAA AGGCCTACGGTTTCTGGAGCAAACCTGTCCCCCACCTGTGACCAGTCACTCTGGGGCAAG CATCACTGGGAAGGGCATAGCCGGAGACCTTTCTCCTAGTGACTGGTAGTCAGTGGGGCA TTTTAGGATGTCAGGGCCCCAGGGTGACATGTGTCCAGCTTTTCTATGGCAGCAGAGGCC TTTCCCTCAGACAAGCTACAAAGTGCCCAGGATGCCATCCACCATGGTCCCCTTCAGTAC CTCACGCATGGTCCCCAGCTTCTCCTAGGATCCCAGTGGCATTTATCAGTGGCCAGCTAC CTGCCAGGCCCGGGCTGGGGCACGGTCTGCGGCCATGAGGCCAGGCCGCCTCCCGCACCC CTACCCCGTGGCAGCAGCATACCTCTGCATTTCTGGAATGTGTGTGCATCAATGATGTTT GTATATTTGAGGCATTTAAAAATCTATTTTCGTTACGAGGGCAAATGAAGAATGAATATT GATCTTAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_030767 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There are 4 nucleotide differences between the OriGene clone and the NCBI reference ORF. OriGene considers these to be polymorphisms and to reflect the natural differences between individuals. These result in the substitution of 2 amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_030767.2, NP_110394.2 |
| RefSeq Size | 5385 bp |
| RefSeq ORF | 4320 bp |
| Locus ID | 80709 |
| UniProt ID | Q7Z591 |
| Gene Summary | Centrosomal protein that plays a key role in cell delamination by regulating microtubule organization (By similarity). Required for the delamination and retention of neural stem cells from the subventricular zone during neurogenesis (By similarity). Also regulates the epithelial-to-mesenchymal transition in other epithelial cells (By similarity). Acts by increasing centrosomal microtubule nucleation and recruiting nucleation factors and minus-end stabilizers, thereby destabilizing microtubules at the adherens junctions and mediating constriction of the apical endfoot (By similarity). In addition, may also act as a transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development (PubMed:11268217). Binds to A/T-rich promoters (PubMed:11268217). It is unclear how it can both act as a microtubule organizer and as a transcription factor; additional evidences are required to reconcile these two apparently contradictory functions (Probable).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein (isoform 1). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208832 | AKNA (Myc-DDK-tagged)-Human AT-hook transcription factor (AKNA) |
CNY 9,848.00 |
|
| RC208832L3 | Lenti ORF clone of Human AT-hook transcription factor (AKNA), Myc-DDK-tagged |
CNY 16,250.00 |
|
| RC208832L4 | Lenti ORF clone of Human AT-hook transcription factor (AKNA), mGFP tagged |
CNY 16,250.00 |
|
| RG208832 | AKNA (tGFP-tagged) - Human AT-hook transcription factor (AKNA) |
CNY 11,448.00 |
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