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Ist1 (NM_001017454) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR201868L4V
- LentiORF®
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Lenti ORF particles, Ist1 (GFP-tagged ORF) - Rat similar to RIKEN cDNA 2400003C14 (RGD1307799), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Ist1 (NM_001017454) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | RGD1307799 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001017454 |
| ORF Size | 1098 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR201868).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001017454.2 |
| RefSeq Size | 2261 bp |
| RefSeq ORF | 1101 bp |
| Locus ID | 307833 |
| Gene Summary | ESCRT-III-like protein involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing. Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST.[UniProtKB/Swiss-Prot Function] |
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