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SHP1 (PTPN6) (NM_002831) Human Recombinant Protein
CAT＃: TP720146
Recombinant protein of human protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 1
View other "SHP1" proteins (8)
|
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CNY 1,800.00
Product images
Specifications
| Product Data | |
| Species | Human |
| Expression cDNA Clone or AA Sequence |
Lys243-Ile541
|
| Tag | C-His |
| Predicted MW | 35.4 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Supplied as a 0.2 um filtered solution of 25mM Tris-HCl, 2mM β-ME, 1mM EDTA, 1mM DTT, 20% Glycerol, pH 7.5. |
| Storage | Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | < 0.1 EU per µg protein as determined by LAL test |
| Reference Data | |
| RefSeq | |
| Locus ID | 5777 |
| UniProt ID | P29350 |
| Cytogenetics | 12p13.31 |
| Synonyms | HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; SHP1 |
| Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Phosphatase, Stem cell - Pluripotency |
| Protein Pathways | Adherens junction, B cell receptor signaling pathway, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC401007 | PTPN6 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC409133 | PTPN6 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY401007 | Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 1 |
CNY 3,080.00 |
|
| LY409133 | Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2 |
CNY 3,080.00 |
|
| PH300728 | PTPN6 MS Standard C13 and N15-labeled recombinant protein (NP_536858) |
CNY 19,520.00 |
|
| PH313896 | PTPN6 MS Standard C13 and N15-labeled recombinant protein (NP_002822) |
CNY 19,520.00 |
|
| TP300728 | Recombinant protein of human protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP313896 | Recombinant protein of human protein tyrosine phosphatase, non-receptor type 6 (PTPN6), transcript variant 1, 20 µg |
CNY 2,900.00 |
Rabbit anti-PTPN6 Polyclonal Antibody
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